32 Best Viruses and Epidemics Movies

It is amazing how much a microscopic virus can multiply and what global problems it causes mankind. The virus movies will show the size of the catastrophe if, God forbid, it happens.


  • IMDB Rating – 6.6
  • Genre: thriller, drama, action
  • Production: USA / 1995
  • Budget: $50,000,000
  • World Box Office: $189,859,560
  • Director: Wolfgang Petersen
  • Starring Dustin Hoffman, Rene Russo, Morgan Freeman, Kevin Spacey, Cuba Gooding Jr, Donald Sutherland, Patrick Dempsey, Zakes Mokae, Malik Bowens, Susan Lee Hoffman

A monkey infected with a dangerous disease comes to America from the African jungle. The epidemiologists from the U.S. Army Research Institute, including Colonel Sam Daniels, urgently fly to the epicenter of infection, where the dangerous virus has already wiped out an entire village.

The purpose of the operation is to prevent its further spread. Bites from an infected animal in the U.S. have already affected several people. To prevent the epidemic a serum made from the material of the monkey whose location is unknown is needed. It’s counting to hours.

The Motaba virus claimed in the film is supposedly more dangerous than Ebola, but it is the Ebola strain that is shown on the screen.

32 Best Viruses and Epidemics Movies

Resident Evil

Resident Evil
  • IMDB Rating – 6.7
  • Genre: horror, action, fantasy
  • Production: USA, Germany / 1995
  • Budget: $33,000,000
  • World Box Office: $102,984,862
  • Directed by: Paul W. S. Anderson
  • Starring Milla Jovovich, Michelle Rodriguez, Eric Mabias, James Purefoy, Martin Crews, Colin Salmon, Ryan McCluskey, Oscar Pierce, Indra Ove, Anna Bolt

This is one of the best zombie apocalypse movies based on the computer game of the same name. A dangerous virus has been released from a giant laboratory deep underground, turning people into bloodthirsty zombies. The demented flesh-eater can become a bite or a small scratch.

The military sends commandos to a secret complex to destroy the hungry monsters, soon joined by Alice, who has lost his memory, and police officer Matt. Only three hours are allotted to destroy the virus.

In the horror film, one of the many zombies was played by the film’s producer, Jeremy Bolt.

The sci-fi action film grossed a record $103,000,000 at the box office at the time.

32 Best Viruses and Epidemics Movies

Cabin Fever

Cabin Fever
  • IMDB Rating – 5.6
  • Genre: horror, drama
  • Production: USA / 2003
  • Budget: $1,500,000
  • World Box Office: $30,553,394
  • Director: Eli Roth
  • Starring Ryder Strong, Jordan Ladd, James DeBello, Serina Vincent, Joey Kern, Erie Vervin, Robert Harris, Hal Courtney, Matthew Helms, Richard Boone.

The school year is over. Five young people decide to rest in the woods, in a cabin. The strange locals don’t bother them. Suddenly, they meet a tramp with rotting lesions on his skin. The boys get rid of the unfortunate man, but they do not know that the poor guy has infected the local body of water.

Tension and fear thicken. The contagious infection, starting with the skin, affects people’s souls as well. Former friends go to extremes to save their skins.

For lack of time, a real police dog, which was unpredictably vicious, was brought in to shoot. The actors were afraid to appear with it in the frame.

32 Best Viruses and Epidemics Movies

28 Days Later

28 Days Later
  • IMDB Rating – 7.6
  • Genre: horror, sci-fi, thriller, drama
  • Production: UK / 2002
  • Budget: $8,000,000
  • World Box Office: $82,719,885
  • Director: Danny Boyle
  • Starring Cillian Murphy, Naomie Harris, Megan Burns, Brendan Gleeson, Christopher Eccleston, Noah Huntley, Luke Mabley, Stuart McQuarrie, Junior Lanyan, Sanjay Rambart

A sci-fi movie about a pandemic that turns humans into insane killers. Inadequate “Greens” infiltrate a primate research center and release one individual. The virus of uncontrolled aggression, entering the bloodstream, infects the body in an instant.

Jim, waking up in the hospital, sees London, mesmerized by its emptiness and silence. Wandering the streets, reading abandoned newspapers, he realizes that the entire population has been evacuated. After meeting the survivors Selena, Frank and his daughter Hannah, they set off toward Manchester, looking for safety. With a group of military men, they hide out in an abandoned house.

According to Time Out magazine, the picture was named the best British film.

Initially, the role of Jim was offered to Leonardo DiCaprio, and Major West to Robert Carlyle.

32 Best Viruses and Epidemics Movies

The Happening

The Happening
  • IMDB Rating – 5.0
  • Genre: Sci-fi, thriller, drama, detective
  • Production: USA, India / 2008
  • Budget: $48,000,000
  • World Box Office: $163,403,799
  • Director: M. Knight Shyamalan
  • Starring Mark Wahlberg, Zooey Deschanel, John Leguizamo, Ashlyn Sanchez, Betty Buckley, Spencer Breslin, Robert Bailey Jr.

High school teacher Elliot Moore and his wife, Alma, try to escape the threat of human extinction. In eastern America, plants begin to secrete a special toxin that pushes people to commit suicide. Mass uncontrolled suicides begin to take place everywhere in the city. Even after leaving the focus of the epidemic, the threat to life does not disappear.

The shooting of the picture lasted 44 days, and 85% of the film’s action takes place in the street.

The main role was written by the director specifically for Mark Wahlberg.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 6.6
  • Genre: Sci-fi, thriller, drama, detective
  • Production: Brazil, Canada, Japan, UK, Italy / 2008
  • Budget: $25,000,000
  • World Box Office: $19,844,979
  • Director: Fernando Meirelles
  • Starring: Julianne Moore, Mark Ruffalo, Gael Garcia Bernal, Danny Glover, Alicia Braga, Yusuke Isei, Jason Bermingham, Eduardo Semirian, Don McKellar, Kika Meirelles

A film-drama about an epidemic based on the novel by Jose Saramago. A strange disease is spreading in the metropolis. People are losing their sight. The first was a young man who suddenly went blind right behind the wheel of a car. His neighbors try to help him, but no one thinks about the infection. The number of blind people is growing exponentially.

In a strange way, one woman avoids infection. The authorities, the city’s residents are quarantined. Abandoned, unwanted people on the reservation set their own rules for a tragic existence. The only seeing woman is forced to become a guide for the sightless.

At first, the director of the film planned to shoot the film in Portuguese, but for fear of losing the audience, abandoned the idea.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 5.9
  • Genre: Sci-fi, action, thriller
  • Production: UK, USA, South Africa, Germany / 2008
  • Budget: $30,000,000
  • World Box Office: $22,211,426
  • Director: Neil Marshall
  • Starring: Rhona Mitra, Bob Hoskins, David O’Hara, Adrian Lester, Rick Warden, Sean Pertwee, Darren Morfitt, MayAnne Boehring, Malcolm McDowell, Caryn Peterson

A fantasy action film with thriller elements. Events in the film unfold in Scotland. A deadly and unexplored virus called “Reaper” has wiped out most of the British population. Without solving the problem, the government isolates the hotbed of infection by building a wall. Finally, the chaos behind the wall is replaced by a dead silence.

But 30 years later, the virus wakes up. To stop the epidemic, authorities send a team of brave fighters led by Major Eden Sinclair to find a vaccine. There they are greeted by a world of brutality, violence and permissiveness. To accomplish their goal and stay alive, the guys will have to fight their way through a real nightmare that has come to life.

In the scene when the special unit penetrates on board the cargo ship, you can notice that on board in large letters it is written in Russian “Первый раз” (First time).

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 6.0
  • Genre: Sci-fi, thriller, drama, adventure
  • Production: USA / 2008
  • World Box Office: $5,802,422
  • Director: David Pastor, Alex Pastor
  • Starring: Lou Taylor Pucci, Chris Pine, Piper Perabo, Emily VanCamp, Christopher Meloni, Kiernan Shipka, Ron McClary, Mark Moses, Josh Berry, Tim Janis

A travel movie about the possibility of a near global catastrophe. A virus has exterminated almost all life on earth. The insidious infection spreads through the air, entering the body through blood and saliva. Fours tries to escape the disease by constantly moving around and avoiding the few contacts.

The foursome – 2 brothers Danny, Brian and girls – Bobby and Kate go to a place where there is no infection – Turtle Beach. But will they manage to survive?

The film sat on the shelf for three years before viewers saw it. There are no zombies rushing after the main characters, which sets it apart from this kind of movie.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 5.9
  • Genre: horror, thriller, sci-fi
  • Production: USA, Spain / 2008
  • Budget: $12,000,000
  • World Box Office: $41,319,906
  • Director: John Eric Dowdle
  • Starring: Jennifer Carpenter, Steve Harris, Jay Hernandez, Jonathon Scheck, Columbus Short, Andrew Fiscella, Rade Sherbegia, Greg Germann, Bernard White, Danya Ramirez

John Dowdle’s picture of viruses and epidemics is reminiscent of a documentary. Paired with her cameraman, TV reporter Angela Vidal travels to a Los Angeles fire station to show how those who protect the city from danger live.

A routine call leads them to a downtown building housing a woman who has contracted an unknown virus. Until all the circumstances are clarified, the authorities close the house and its inhabitants to quarantine. Now it’s up to the people to decide how to save themselves, because no one really cares about their lives.

There is no musical accompaniment in the film.

Experts note that the symptoms of rabies in the film are depicted with clinical precision.

32 Best Viruses and Epidemics Movies

I Am Legend

I Am Legend
  • IMDB Rating – 7.2
  • Genre: fantasy, action, thriller, drama, adventure
  • Production: USA / 2007
  • Budget: $150,000,000
  • World Box Office: $585,349,010
  • Director: Francis Lawrence
  • Starring: Will Smith, Alicia Braga, Charlie Tahan, Sally Richardson-Whitfield, Willow Smith, Darrell Foster, April Grace, Dash Mayock, Joanne Numata.

The movie is about a global epidemic that wiped out almost all humans. Robert Neville, a medic, a lieutenant colonel, lives in deserted New York, eats canned food and walks with his faithful dog. Three years have passed since the human race was exterminated by a terrible virus.

Those who survived have turned into vampire-like foul creatures. At night they prey on Robert, and Neville catches them-he needs test subjects to test a plague vaccine. The man manages to create a serum, but how do you get it to the survivors?

32 Best Viruses and Epidemics Movies

The Invasion

The Invasion
  • IMDB Rating – 5.9
  • Genre: Sci-fi, thriller
  • Production: USA, Australia / 2007
  • Budget: $80,000,000
  • World Box Office: $40,170,558
  • Director: Oliver Hirschbigel, James McTeague
  • Starring: Nicole Kidman, Daniel Craig, Jeremy Northam, Jackson Bond, Jeffrey Wright, Veronica Cartwright, Joseph Sommer, Celia Weston, Roger Reece, Eric Benjamin.

The plot of the sci-fi horror film unfolds in Washington, DC. After an alien invasion of Earth, an epidemic begins. The virus from the depths of space, getting on people, not only changes their DNA code, but also the essence.

People become strangers to feelings of fear, anger, joy and kindness. The only way not to become like a zombie is not to sleep, because the aliens infiltrate the bodies in their sleep. The psychiatrist Carol and the scientist Driscol try to find a solution to the problem.

The film had to be additionally reshot because the producers of the film felt it was not enough of a “thriller”.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 7.1
  • Genre: Horror, drama, melodrama
  • Production: Korea Southern / 2009
  • Budget: $5,000,000
  • World Box Office: $13,770,623
  • Director: Park Chang-uk
  • Starring: Sung Kang-ho, Kim Ok-pin, Shin Ha-kyung, Park In-whan, Oh Dal-soo, Sung Yeon-chan, Mercedes Cabral, Ra Mi-ran, Eric Ebony, Hwang Seul-hee

Sang-ho, a priest respected by his parishioners, volunteers to test an experimental vaccine for a terrible, incurable disease. Sang-ho’s body fails and he dies. But suddenly he suddenly comes to life.

A miracle happens: the priest’s eyesight improves, the ability to fly appears and he recovers quickly. Thanks to this, the preacher became famous. But the virus takes over his body and creates an irresistible and uncontrollable desire for human blood.

At the 2009 Cannes Film Festival, the film won the Special Jury Prize.

32 Best Viruses and Epidemics Movies

Black Death

Black Death
  • IMDB Rating – 6.4
  • Genre: Detective, thriller, drama, adventure
  • Production: Germany, UK / 2010
  • Budget: $10,800,000
  • World Box Office: $265,318
  • Director: Christopher Smith
  • Starring: Sean Bean, Eddie Redmayne, Carice van Houten, John Lynch, Tim McInerney, Kimberly Nixon, Andy Nyman, David Warner, Johnny Harris, Iman Elliott

The Middle Ages, England under the rule of the Black Death, people are dying by the thousands. The servants of the local monastery have no time to bury the inhabitants. A detachment of soldiers with the young monk Osmund travels to the only village where the plague has not yet reached.

The locals are rumored to worship the devil and necromancy is rampant there. The goal of the warriors is to track down the one who can bring the dead back to life, capture and execute the chief satanist. But nothing good awaits them along the way.

It is worth noting that in the 14th century, monasteries made candles from fat, not from wax, as shown in the film.

32 Best Viruses and Epidemics Movies

Stake Land

Stake Land
  • IMDB Rating – 6.5
  • Genre: horror, sci-fi, drama
  • Production: USA / 2010
  • Budget: $650,000
  • World Box Office: $405,380
  • Director: Jim Mickle
  • Starring: Connor Paolo, Gregory Jones, Tracy Howell, Daniel Harris, Nick Damici, James Godwin, Tim Howes, Marianne Hagan, Stuart Rudin, Adam Scarimbolo

A terrible plague struck the cities – an epidemic of vampirism. People have mutated and become “the living dead. The monsters operate at night, for they fear the sun and fire. The South of America is completely overrun by them.

But where there are vampires, there are also vampire hunters. Teenager Martin, whose family has been killed by the creatures, meets one of them named Mister. Together they embark on a journey to New Eden, a place across the Canadian border that is free of bloodsuckers.

The low-budget horror film won awards at film festivals in Montreal, Toronto and Amsterdam.

The actors had to sit for two hours at a time while they applied vampire makeup.

32 Best Viruses and Epidemics Movies

The Crazies

The Crazies
  • IMDB Rating – 6.5
  • Genre: horror, thriller, detective
  • Production: USA, UAE / 2010
  • Budget: $20,000,000
  • World Box Office: $54,806,823
  • Director: Breck Eisner
  • Starring: Timothy Olyphant, Radha Mitchell, Joe Anderson, Daniel Panabaker, Christy Lynn Smith, Brett Rickaby, Preston Bailey, John Aylward, Joe Regan, Glenn Morshower

In the small town of Ogden Marsh, local sheriff David Dutton, at one of the baseball team’s games, sees a local man wandering across the field with a shotgun in his hands. The aggressive man does not respond to calls to drop the gun. The sheriff has to shoot. A little later, another series of shocking events takes place.

The town is under attack from the local river, which is the source of the drinking water. At the bottom of the river bed, covered in algae, lies an airplane carrying a deadly cargo – a dangerous virus. The military promptly quarantines the city and does not tolerate the infected.

The American film about the virus is a remake of “The Crazies”, a film made in the early 1970s.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 5.8
  • Genre: Thriller, Drama
  • Production UK / 2011
  • Worldwide box office receipts: $4,498
  • Directed by Carl Tibbetts
  • Starring: Cillian Murphy, Thandiwe Newton, Jamie Bell, Jimmy Yuill, Marilyn Mantle

Journalist Kate and architect Martin, each after experiencing a personal tragedy, seclude themselves on an island. They live in perfect harmony, until a bloodied military man shows up at their house almost alive.

The wounded man regains consciousness and tells them that a terrible virus is rampant on the mainland, wiping out half the population off the island, and to survive, no one is allowed to leave safe territory. The couple finds themselves completely at the mercy of the stranger.

Retreat is the feature film debut of Carl Tibbetts, the future director of Black Mirror and Hemlock Grove.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 6.8
  • Genre: Thriller, Drama
  • Production: USA, UAE / 2011
  • Budget: $60,000,000
  • Worldwide Box Office: $136,515,867
  • Directed by Steven Soderbergh
  • Starring: Matt Damon, Laurence Fishburne, Jude Law, Kate Winslet, Marion Cotillard, Gwyneth Paltrow, Bryan Cranston, Jennifer Elle, Sanaa Lathan, Elliott Gould.

A woman who recently returned from Hong Kong dies of a strange virus. With terrible speed, the epidemic spreads to all continents of the Earth. The number of victims is steadily increasing.

An international group of doctors is trying to stop the spread of the deadly virus and localize the hotbed of infection. Nayavu signs of a global pandemic and it is not only a threat to life for mankind, but also the turnover of huge sums of money.

Today, the movie is being called prophetic, and the number of viewings of it since the coronavirus emerged is off the charts.

32 Best Viruses and Epidemics Movies

The Bay

The Bay
  • IMDB Rating – 5.7
  • Genre: Horror, Fantasy, Thriller
  • Production USA / 2012
  • Worldwide Box Office: $1,581,252
  • Director: Barry Levinson
  • Starring: Will Rogers, Kristen Connolly, Kater Donoghue, Frank Diehl, Stefan Kanken, Christopher Denham, Nancy Aluka, Kimberly Campbell, Beckett Clayton-Luke, Dave Hager

On Independence Day, a biological disaster occurs in a provincial town in the United States on the shores of a bay. Due to the discharge of chicken litter from a local farm into the bay, marine parasites mutate in the water.

The whole town is struck by a terrible panic due to an outbreak of an unknown disease. People are distraught, authorities are powerless, medics don’t know how to help the victims. The worst begins when the first fatality occurs.

Director B. Levinson shot the film in the genre of mocumentary (pseudo-documentary).

32 Best Viruses and Epidemics Movies

World War Z

World War Z
  • IMDB Rating – 7.0
  • Genre: Horror, Fantasy, Action, Adventure
  • Production USA / 2013
  • Budget: $190,000,000
  • Worldwide Box Office: $540,007,876
  • Director: Marc Forster
  • Starring: Brad Pitt, Mireille Inos, Sterling Jerins, Abigail Hargrove, Daniela Cartes, Fana Mokoena, Pierfrancesco Favino, Peter Capaldi, Moritz Bleibtroi, Ruth Negga

Former UN employee Jerry Lane, leads a measured life, which in an instant comes to an end. An invasion of the living dead begins. Zombies overnight become a reality – and it is a terrible threat to humanity.

Rotting, half-decomposed, invulnerable monsters are taking over the continents. In search of an antidote, Lane and her group travel the world overrun by the epidemic. The fate of humanity hangs in the balance, and Jerry is the only hope.

On June 20, 2013, the film opened the 35th Moscow International Film Festival.

K. Khabenksky’s name is in the credits, but, unfortunately, the scenes with his participation were cut from the final release of the film.

32 Best Viruses and Epidemics Movies

The Last Days

The Last Days
  • IMDB Rating – 6.1
  • Genre: Horror, Fantasy, Thriller
  • Production: Spain, France / 2013
  • Budget: €5,000,000
  • Worldwide Box Office: $4,343,816
  • Director: David Pastor, Alex Pastor
  • Starring: Kim Gutierrez, Jose Coronado, Marta Etura, Leticia Dolera, Mikel Iglesias, Ivan Massaguet, Pere Ventura, Luis Soler, Hvida, Farah Hamed.

Spain, Madrid, 2013. The life of a megapolis goes on its usual rut – people wake up, go to work, scandalize, fall in love. But a collapse comes – a mysterious epidemic comes to Earth.

The world is at the mercy of agoraphobia – fear of open space. People go mad, the streets become empty, and there is filth and stench everywhere. Survivors are hiding in buildings, in subway tunnels. Mark is at the office when the epidemic hits. But he needs to be home with his pregnant wife. Mark’s arduous journey takes him through underground utilities.

A movie-catastrophe, a chilling thriller created by the masters of this genre – the Pastor brothers.

32 Best Viruses and Epidemics Movies

The Flu

  • IMDB Rating – 6.6
  • Genre: Action, Thriller, Fantasy
  • Production: South Korea / 2013
  • Worldwide box office receipts: $19,775,853
  • Director: Kim Sung-soo
  • Starring: Jang Hyuk, Soo-ae, Park Min-ha, Yoo Hae-jin, Lee Hee-joon, Ma Dong-seok, Lee Sang-yeop, Cha In-pyo, Kim Gi-hyun, Park Hyo-ju

In a suburb of Seoul, the population becomes infected with a bird flu virus. Two bandit brothers find a pile of illegal immigrants in a van and one survivor who escapes. While they catch the migrant, they unknowingly spread the mutated virus through the neighborhood.

The contagion is airborne and spreads quickly. An emergency has been declared, panic is all around, people are trying to escape by any means. In this chaos, Ji Gu, a lifeguard, risks his life to help a girl he likes and her infected daughter. The government makes a series of fatal decisions to prevent the entire country from dying.

32 Best Viruses and Epidemics Movies

The Strain

The Strain
  • IMDB Rating – 7.3
  • Genre: Horror, Fantasy, Thriller, Drama
  • Production: USA, Canada, Mexico / 2014
  • Directed by: J. Miles Dale, Kevin Dowling, Deran Sarafian, Phil Abraham
  • Starring: Corey Stoll, Mia Maestro, David Bradley, Richard Zammel, Sean Estin, Jonathan Hyde, Kevin Duran, Jack Kesey, Natalie Brown, Ben Hyland

A plane full of dead people has landed in New York. To find out the circumstances of mass death, scientists headed by epidemiologist Ephraim Goodweather come on board. It becomes clear that the passengers are infected with the virus of vampirism, which threatens humanity with extinction.

Panic grows in the society. The protagonist tries to get to the truth, but instead of answers he gets only questions. The further Goodweather plunges into solving the mystery, the more mysterious circumstances appear.

The series premiered on July 13, 2014 on the FX television network.

Lauren Lee Smith was originally confirmed for the role of Kelly, but Natalie Brown played the role in the movie.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 5.5
  • Genre: Horror, Fantasy, Drama
  • Production: USA / 2015
  • Worldwide box office receipts: $551,760
  • Directed by: Henry Joost, Eriel Shulman
  • Starring: Sofia Black-D’Elia, Analie Tipton, Travis Tope, Michael Kelly, Mashin Gun Kelly, John Cothran, Stoney Westmold, Lynsey Gray, Judyann Elder, Philip Labes

The action of a fantastic movie about the spread of the virus takes place in a small town, which is located in a picturesque valley surrounded by mountains. The heroines are two sisters – Stacy, Emma and their father. They have recently moved to this town and are trying to find their place in the community.

In this paradise corner there is an epidemic of an unknown virus that eats people’s bodies and turns them into zombies. The authorities impose a quarantine, entry and exit are forbidden. The girls try to survive in conditions when the non-humans are becoming more numerous hour by hour.

32 Best Viruses and Epidemics Movies

93 Days

93 Days
  • IMDB Rating – 6.0
  • Genre Drama
  • Production: Nigeria / 2016
  • Budget: $1,500,000
  • Director: Steve Goukas
  • Starring: Bimbo Akintola, Danny Glover, Alastair Mackenzie, Tim Reid

A virus – the most dangerous virus the world has ever known – is discovered in a Nigerian metropolis. Patrick Sawyer, an American diplomat, arrives in Lagos. The man’s condition worsens and he is immediately taken to Sawyer Medical Center. The patient’s tests confirm the presence of Ebola.

Journalists around the world begin to broadcast news about it. Nigeria immediately prepares to fight the epidemic. This is the story of the sacrifices made by the men and women who risked their lives to contain the virus and prevent the epidemic.

The movie is dedicated to Ameilo Adadevoh, a Nigerian doctor who played a major role in containing Ebola in the country.

32 Best Viruses and Epidemics Movies

Train to Busan

Train to Busan
  • IMDB Rating – 7.6
  • Genre: Horror, Action, Thriller
  • Production: Korea South / 2016
  • Budget: $8,500,000
  • Worldwide Box Office: $96,660,013
  • Director: Young Sang-ho
  • Starring: Gun Yoo, Ma Dong-seok, Jung Yoo-mi, Kim Soo-an, Kim I-seong, Choi Woo-shik, Ahn So-hee, Choi Gwi-hwa, Jung Sog-yong, Ye Soo-jong

A virus epidemic is gradually sweeping the country, causing people to go mad and devour their own kind. A high-speed train bound for Busan has become a temporary refuge for the few escapees from the mysterious epidemic in Seoul.

The random passengers didn’t think their ticket on this express train would be a lucky one. How long will their luck last? All events take place directly on the train, or at the stops. Passengers should try to stay alive.

This is the first feature film directed by Yong Sang-ho, who has only directed animated films before. South Korea’s highest-grossing movie.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 6.3
  • Genre: Drama, Horror
  • Production: Australia / 2017
  • Worldwide Box Office: $56,385
  • Director: Ben Howling, Yolanda Ramke
  • Starring: Simon Landers, Martin Freeman, Marley Jane McPherson-Dobbins, Lily Anne McPherson-Dobbins, Finlay Sjoberg, Nova Sjoberg, Susie Porter, Ella Barter, Aidan Squire, Alexandra Schulze

Humanity is on the verge of extinction. The few survivors are trying to adapt to the new living conditions. A small family escapes from the infected on a houseboat floating on the river.

A man’s wife dies, he is left with an infant in his arms, and becomes the only person who can help his daughter move on with her life. But he, too, is bitten. The father has 48 hours left to find guardians for the baby girl.

The film is based on the 2013 short film of the same name, which garnered almost 13 million views on YouTube.

5 weeks of filming in South Australia were accompanied by bad weather.

32 Best Viruses and Epidemics Movies

It Comes at Night

It Comes at Night
  • IMDB Rating – 6.2
  • Genre: Horror, Drama
  • Production: USA / 2017
  • Budget: $5,000,000
  • Worldwide Box Office: $19,735,344
  • Director: Trey Edward Schultz
  • Starring: Joel Edgerton, Christopher Abbott, Carmen Ejogo, Riley Keough, Calvin Harrison, Griffin Robert Faulkner, David Pendleton, Chase Joliet, Mick O’Rourke

The movie is a psychological horror about post-apocalyptic consequences. The world is struck by a sinister epidemic that spreads rapidly and kills people in a matter of days. Death is all around.

For the sake of their salvation, the family hides in an abandoned house in the thicket of the forest. In order not to be infected, Paul has established strict rules for himself, his wife Sarah and teenage son Travis to ensure their survival. The family shuns outsiders, but one day strangers show up on their doorstep.

Professional critics consider young director Trey Edward Schultz’s horror picture one of the best of the last decade.

32 Best Viruses and Epidemics Movies

Bird Box

Bird Box
  • IMDB Rating – 6.6
  • Genre: Horror, Fantasy
  • Production: USA / 2018
  • Budget: $19,800,000
  • Director: Susanne Bier
  • Starring: Sandra Bullock, Trevante Rhodes, John Malkovich, Sarah Paulson, Jacki Weaver, Rosa Salazar, Danielle Macdonald, Lil Rel Howery, Tom Hollander, Mashin Gun Kelly

5 years the world is plunged into chaos: seeing something, people commit suicide. In the new world, the most important thing is that you cannot open your eyes. Not having sight itself is a terrible phenomenon, because people are used to relying on this sense organ.

Malorie, a pregnant artist divorced with two five-year-old children, in order to save herself, goes in search of the surviving community and brings her parrots with her. The protagonist has a long and dangerous journey ahead of her.

The world premiere took place in November 2018 at the American Film Institute Festival.

Sandra Bullock spent half of the shooting days blindfolded.

32 Best Viruses and Epidemics Movies

The Hot Zone

The Hot Zone
  • IMDB Rating – 7.3
  • Genre: Fantasy, Thriller, Drama
  • Production: USA, Canada, UK / 2019
  • Director: Nick Murphy, Michael Appendahl
  • Starring: Julianna Margulies, Noah Emmerich, Topher Grace, Liam Cunningham, Paul James, Lenny Arroyo-Platt, James D’Arcy, Robert Wisdom, Nick Searcy, Mark Kelly

The movie shows exactly how the deadly virus got so close to people. In 1989, the Ebola virus enters the United States. Lt. Nancy Jacks risks her health and life by testing a sample of the deadly virus.

To find out where the source of the infection is and prevent an outbreak, Jax enlists the help of Dr. Wade Carter, an Ebola expert who has been forgotten by the world, a professor who has offended the entire world.

The first of 6 episodes premiered in May 2019 on National Geographic. The plot of this mini-series is based on real events when Ebola was first reported in America.

32 Best Viruses and Epidemics Movies

Vongozero: The Outbreak

Vongozero: The Outbreak
  • IMDB Rating – 7.3
  • Genre: Drama, Thriller
  • Production: Russia / 2019
  • Director: Pavel Kostomarov
  • Starring: Kirill Kyaro, Victoria Isakova, Maryana Spivak, Alexander Robak, Yuri Kuznetsov, Natalia Zemtsova, Victoria Agalakova, Eldar Kalimulin, Saveliy Kudryashov

A disaster movie about an epidemic. A tough drama against the backdrop of the apocalypse. In the capital of Russia discovered a terrible virus that provokes mass suicides. Sergei with a new lover, her autistic child, ex-wife, native son and random fellow travelers try to cross the quarantine border to save everyone.

On a deserted island in Karelia stands a hunting lodge where the company will be able to continue their existence. But the path to a new life will be difficult. The heroes flee not only from a global catastrophe, but also from a personal family drama.

Vongozero: The Outbreak is an abridged version of the series that was presented at the 41st Moscow International Film Festival.

32 Best Viruses and Epidemics Movies


  • IMDB Rating – 4.7
  • Genre: Thriller, Drama, Melodrama
  • Production: USA / 2021
  • Worldwide box office receipts: $620,836
  • Director: Adam Mason
  • Starring: KJ Apa, Sofia Carson, Craig Robinson, Bradley Whitford, Peter Stormare, Elpidia Carrillo, Alexandra Daddario, Leah McHugh, Paul Walter Hauser, Demi Moore

In the year 2024, the Covid-23 virus is spreading through the city. Infected people are forcibly dragged from their homes and sent to sinister quarantine camps. The population is locked up, communicating via the internet and drones.

Nico, a courier with a rare immunity to the disease, meets a girl, Sara, and dreams of leaving for the free zone. The lives of a disabled ex-military man and a local prostitute come together in the hope of salvation and a miracle.

The sci-fi thriller is directed by Adam Mason in the romantic thriller-antiutopia genre.

32 Best Viruses and Epidemics Movies

Locked Down

Locked Down
  • IMDB Rating – 5.2
  • Genre: Melodrama, Comedy, Crime
  • Production: UK, USA / 2021
  • Worldwide Box Office: $346,899
  • Director: Doug Lyman
  • Starring: Anne Hathaway, Chiwetel Ejiofor, Dewley Hill, Jasmine Simon, Frances Ruffel, Bobby Schofield, Tallulah Grieve

A movie about an epidemic in the genre of melodrama with elements of comedy and crime. In London, the epidemic of the coronavirus has closed most of the residents at home. Among them are Linda, who heads a regional branch of an international company, and Paxton, a driver of a courier service.

The couple has a protracted crisis in their personal relationship. Deciding to resuscitate them, they intend to carry out a robbery of a jewelry store in the capital’s famous Harrods department store.

It premiered on January 14, 2021 on the HBO Max streaming service.

A romantic comedy directed by Doug Lyman from a screenplay by Steven Knight.

32 Best Viruses and Epidemics Movies

Other Virus Movies

  • Patient Zero (2018)
  • Cell (2014)
  • Pandemic (2016)
  • Twelve Monkeys (1995)
  • Masque of the Red Death (1989)
  • Epidemic (1987)
  • The Cassandra Crossing (1976)
  • Stigma (1972)
  • The Andromeda Strain (1970)
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Анна Румянцева
Anna Rumyantseva

Author, editor and filmmaker.

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